Sep 2026
Population-scale immune multiome atlas reveals regulatory disease mechanisms.
Masahiro Kanai, T. Delorey, Jarno Honkanen et al.
· Nature · 0 citations
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Aug 2026
Genomic dimensions deconstruct the clinical heterogeneity of bipolar disorder
Bipolar disorder’s genetic architecture appears hierarchical—a general liability resolving into dimensions of course and comorbidity, beyond subtypes, beyond subtypes.
Tracey van der Veen, M. Tesfaye, J. M. K. Yang et al.
· Research Square · 0 citations
Aug 2026
Distinguishing different psychiatric disorders using DDx-PRS
Despite great progress on case–control polygenic prediction, an unmet need remains for a method that genetically distinguishes clinically related disorders (e.g., schizophrenia (SCZ) versus bipolar disorder (BIP) versus major depressive disorder (MDD) versus controls). We introduce differential diagnosis–polygenic risk...
W. Peyrot, G. Panagiotaropoulou, L. O. Olde Loohuis et al.
· Nature Genetics · 0 citations