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Review Open access Sep 2026

Efficacy and safety of T-DXd versus Other HER2-targeted therapies in second-line and later settings for HER2-positive metastatic breast cancer: A Bayesian network meta-analysis

Background HER2-positive advanced breast cancer remains challenging after trastuzumab-based therapy because available regimens differ in survival, response, and toxicity. We compared therapies used in second-line and later settings. Methods This PRISMA-NMA-compliant review was registered with PROSPERO (CRD420251244047)...

Yu Xiao, Jing Fu, Juan Li et al. · 0 citations
Open access Sep 2026

Folate receptor-positive circulating tumor cells as a potential biomarker for breast cancer diagnosis

Objectives: This study investigated the potential of folate receptor-positive circulating tumor cells (FR+CTCs) as a non-invasive biomarker for breast cancer diagnosis and clinical stratification. Materials and Methods: Between January 2024 and October 2024, 179 breast cancer patients and 38 patients with benign breast...

Juan Li, Jing Fu, Dan-Dan Zhang et al. · 0 citations
Open access Sep 2026

Depression-related gene signature characterizes prognostic subtypes and therapeutic sensitivities in colorectal cancer

A risk stratification framework comprising 14 DRGs that showed moderate prognostic performance in CRC was developed, and METTL9 was identified as overexpressed in CRC tissues, showed association with unfavorable clinical outcomes, and exhibited enhanced proliferative and migratory capacities in CRC cells.

Qiang Xu, Gang Hu, Ning-Jie Sun et al. · 1 citation

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