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Author

G. Halliday

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2 papers indexed here

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#gene editing Open access Oct 2026

Astrocyte-Specific dsRNA–ADAR1 Signalling Links Innate Immunity to Complement Activation in Parkinson’s Disease

Astrocytes is identified as a central site of relative dsRNA accumulation and ADAR1 p150 induction in the PD cortex, and the selective coupling of dsRNA sensing to complement activation in astrocytes highlights a cell-type-specific innate immune pathway that is constitutively present rather than induced by disease.

Yang Liu, G. Halliday, Yu-Hong Fu · 0 citations
Review Jul 2026

Astrocytic lipid dysregulation as an early driver of neurodegeneration

Evidence is assessed that astrocytic lipid metabolism is not solely protective or pathological but has instructive physiological roles and that astrocytic lipid dysregulation is an early driver of neurodegeneration, and targeting of astrocytic lipid homeostasis represents a promising strategy for preventing or minimizi...

W. S. Kim, G. Halliday · 1 citation

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