G. Calin

AI-integrated RNA therapeutics in precision oncology.

RNA therapeutics can silence oncogenic transcripts, modulate RNA processing, restore protein expression, or encode tumor antigens. Their development, however, is constrained by target selection, molecular design, delivery, immunogenicity, and inter-patient heterogeneity. Artificial intelligence (AI) is increasingly app...

Target-Directed miRNA Degradation: Mechanisms and Significance.

The emerging roles of non-coding RNAs in cancer.

This review examines how different types of ncRNAs contribute to cancer initiation, progression, and treatment resistance, and assesses their potential as diagnostic markers, prognostic factors, and therapeutic targets.