Author

G. Balmus

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

#gene editing Open access Oct 2026

Prime editing enables high-throughput identification and characterization of selective MutSβ inhibitors

DNA mismatch repair (MMR) maintains genome stability but paradoxically drives expansion of pathogenic repeats responsible for trinucleotide repeat disorders. Attenuating repeat instability through targeted inhibition of MMR is therefore a therapeutic strategy of interest; however, progress is constrained by a lack of r...

Yangwode Jing, Jun Yan, Denny Yang et al. · bioRxiv · 0 citations

Open access Aug 2026

Targeting epigenetic regulators induces transcription-replication conflicts to overcome ATR inhibitor resistance

Abstract Many cancer cells exhibit elevated replication stress and are highly dependent on ataxia telangiectasia and Rad3-related (ATR) kinase activity to maintain genomic stability and survival. While ATR inhibitors (ATRi) have great promise as therapeutic agents, intrinsic or acquired resistance will likely be a sign...

Samah W. Awwad, Holly Barber, Josie Coulthard et al. · Nucleic Acids Research · 0 citations