Faranak Hatami

Asymmetric Focal Loss Improves Graph Neural Network Prediction of Drug-Pair-Associated Polypharmacy Side Effects

Accurate prediction of drug-pair-associated polypharmacy side effects remains an important challenge in computational pharmacovigilance. Standard binary cross-entropy (BCE) may provide insufficient emphasis on difficult positive examples. We evaluated ClinicalFocal, an asymmetric focal-loss function that assigns differ...