Background/Objectives: Prospective studies have reported associations between systemic inflammatory biomarkers and colorectal cancer (CRC) risk, but whether these reflect a causal role of inflammation or responses to preclinical disease remains uncertain. Methods: Using data from 383,850 UK Biobank participants (aged 4...
F. Safizadeh, T. Gwenzi, Marko Mandic et al.· Cancers· 0 citations
BACKGROUND
The concurrent rise in metabolic syndrome (MetS) and the changing age profile of colorectal cancer (CRC) necessitates clarifying the heterogeneity in their association across demographic groups. This study aimed to define the precise age- and sex-specific associations between MetS and CRC risk, addressing a...
Zi-Lin Luo, F. Safizadeh, Marko Mandic et al.· British Journal of Cancer· 0 citations
This pooled analysis of 15,731 cases showed that nulliparity, age at menopause, MHT, and BMI have independent, dose-response associations with ER, PR, and grade, clarifying patterns of etiologic heterogeneity.
Daniel Adams, Amber N. Hurson, T. Ahearn et al.· Journal of the National Canc...· 0 citations
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