Author

F. Cyprian

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Open access Oct 2026

Comparative evaluation of antifibrotic activity of Salvadora persica extracts in CCl4-induced liver fibrosis in rats by reducing oxidative stress and inflammation via transcriptional modulation associated with TGF-β1/Smad signaling pathway

Plant Salvadora persica (SP) is well-known for its pharmacological activities, including its role in oral hygiene. In the present study, we investigated, the in vivo comparative hepatoprotective potential of SP root extracts against chronic liver injury fibrosis. In Wistar albino rats, liver fibrosis was induced...

Fouzia Latif, Bilal Ahmed, H. Alkhathlan et al. · Frontiers in Pharmacology · 0 citations

#gene editing Review Aug 2026

Gene-edited hypoimmune islets as a cure for type 1 diabetes: a review of the immunological challenges.

Current preclinical and clinical evidence from 2019 to 2026 for gene-edited hypoimmune islets is critically evaluated, highlighting key immunological vulnerabilities that may emerge over time and whether these long-term challenges can be overcome.

Ahmed Hassanein, F. Cyprian, Saghir Akhtar · Expert Opinion on Biological... · 0 citations