Author

Eva Kowalinski

2 papers indexed here

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Open access Oct 2026

The RNA helicase KREH2 directly binds the RESC1-RESC2 complex in trypanosomatid mitochondrial RNA editing

Trypanosomatids are medically important single-celled eukaryotic protists with exceptional RNA biology. They display highly unusual RNA biogenesis pathways, notably mitochondrial RNA editing, an essential post-transcriptional process transforming cryptic primary transcripts into functional mRNAs. Large multiprotein ass...

Rutuja Yelmar, L. G. Dolce, L. Tengo et al. · bioRxiv · 0 citations

#gene editing Open access Sep 2026

The C-terminus of the KREH1 helicase is important for RNA binding and association with mitochondrial RNA editing complexes in T. brucei

Mitochondrial pre-mRNA editing in kinetoplastids, a clade that includes human-infective parasitic protists such as Trypanosoma and Leishmania, is required to produce translatable, functional gene products from otherwise nonfunctional mitochondrial precursor transcripts of essential respiratory chain complex subunits. R...

Rutuja Yelmar, L. Tengo, F. Stein et al. · bioRxiv · 0 citations