#gene editing
Aug 2026
Gene editing of alveolar organoids reveals AT2 dysfunction due to endosomal SFTPC accumulation.
Endosomal dysfunction and polarity loss are established as drivers of SFTPC-I73T-mediated epithelial injury and mechanisms that may underlie AT2 dysfunction in disease more broadly are highlighted.
E. Rutherford, Da-Wei Sun, Kyungtae Lim et al.
· American Journal of Respirat... · 0 citations