Protocol for non-viral HDR-based CRISPR/Cas9 platform for small custom editing in primary T cells
CRISPR/Cas9 enables precision gene editing via homology-directed repair (HDR) for mutation correction and disease modelling. Here we present a customizable T cell single nucleotide variant (SNV) correction platform based on non-viral HDR, previously described in Mamia et al. Precision T Cell Correction Platform for...
Katariina Mamia, Anniken Solveig Matheson Sollano, Vanja Lundberg et al.
· Frontiers in Genome Editing · 0 citations