Programmable RNA-Guided DNA Recombination: Mechanisms, Engineering, and Applications
This comparative framework highlights a broader transition from programmable sequence modification toward direct engineering of genomic architecture, while identifying recognition-site constraints, mismatch-tolerant recombination, unintended recombination products, delivery, and genome-wide specificity as key translati...
A. A. Ali Agha, Dima Hattab, Athirah Bakhtiar et al.
· Biomedicines · 0 citations