D. Barch

Reliability of computational versus noncomputational metrics of working memory and episodic memory in serious mental illness

Computational models can be used to decompose overall behavior into individual parameters that are designed to isolate specific cognitive and neural processes and provide new information about psychiatric disorders. However, it is not yet clear whether these computational parameters have sufficient reliability to repla...

Journal Pre-proof Distinct Attentional Control Profiles during Language Comprehension in Major Mental Health Disorders

Journal Pre-proof Specific, Replicable Behavioral and Neural Correlates of Sensory Over-Responsivity in Childhood

Youth Autistic Traits and Brain Activation States During Socioemotional Processing

Objective: Different aspects of social-emotional processing are linked to unique whole-brain patterns of neural activity termed ‘activation states’. Autistic traits (ATs) in youth include impairments in socio-emotional processing that vary depending on age and co-morbidity. Characterizing differences in activation stat...

Modeling decision dynamics disentangles working memory, cognitive control and reinforcement learning and reveals clinical differences

It is shown that jointly modeling decision dynamics – accounting not only for choices but also response time distributions, together with hierarchical Bayesian parameter estimation – improves the ability to disentangle separable learning and cognitive control processes.

Intergenerational epigenetic signatures of prenatal adversity and their role in emerging child psychopathology

PSD was associated with epigenetic signatures at birth, with a subset of associations persisting across early childhood and converging on cellular stress response biology, suggesting differential biological embedding of structural versus psychological dimensions of adversity.

Functional brain network correlates of pubertal timing and depressive symptoms in preadolescence.

BACKGROUND Variation in pubertal maturation relative to same-age, same-sex peers (pubertal timing) has been linked to increased risk for depressive symptoms during adolescence. This developmental period is also characterized by substantial reorganization of functional brain networks. However, how pubertal timing relate...