A PepFect14 analog improves non-viral CRISPR delivery in primary human cells to facilitate genome editing and repair.
A PepFect14 analog is employed to deliver high-fidelity Cas9-ribonucleoproteins and non-viral repair templates into primary human skin cells to mediate gene editing and repair targeting genes underlying the group of genetic skin blistering disorders epidermolysis bullosa (EB).
A. du Rand, Courtney Masterson, Daniel J Verdon et al.
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