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Charles R. Gerfen

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#reinforcement learning Open access Sep 2026

Cholinergic-dependent dopamine signals in mouse dorsomedial striatum are regulated by frontal but not sensory cortices

Everyday decisions depend on associations between sensory stimuli, actions, and outcomes. The striatum supports these sensorimotor associations through dopamine-dependent plasticity. Recent work has characterized a local striatal microcircuit in which cholinergic interneurons (CINs) modulate dopamine release via activa...

Hannah C. Goldbach, Rachele Rimondini, Evan S. Swanson et al. · 0 citations

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