Chao Liang

Screening and identification of B-cell epitopes on the gH protein of varicella-zoster virus

Development and Epitope Characterization of Monoclonal Antibodies Targeting the Rabies Virus P Protein

Rabies is a fatal zoonotic disease caused by rabies virus (RABV), resulting in approximately 59,000 deaths annually worldwide and posing a serious threat to public health. The RABV phosphoprotein (P protein) plays crucial roles in viral replication, transcription, and immune antagonism; however, its immunogenic propert...

Characterization of a monoclonal antibody recognizing a conserved linear neutralizing epitope of pseudorabies virus gB protein

This work clarifies the molecular basis of PRV neutralization and identifies a conserved epitope, which upon further validation could serve as a diagnostic candidate and inform antiviral research.

Identification of a novel conserved B-cell epitope in the glycoprotein of rabies virus

This study identifies a novel, highly conserved with conservative substitutions linear B-cell epitope on the RABV glycoprotein, providing a precise molecular target for the rational design of next-generation epitope-based vaccines and specific diagnostic tools.

Identification and computational analysis of B-cell epitopes on the hemagglutinin protein of the H3N2 influenza virus

Findings expand the current understanding of HA epitopes and provide a theoretical basis for developing IAV subunit vaccines and highly sensitive detection methods.