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Open access Aug 2026

Oncologic Outcomes in a Contemporary “PROTEUS-like” Cohort of High-risk Prostate Cancer Treated with Radical Prostatectomy Without Neoadjuvant Hormonal Therapy

Take Home Message In men meeting strict PROTEUS high-risk criteria, an upfront radical prostatectomy strategy was associated with substantial biochemical recurrence and metastatic progression. These contemporary outcomes provide a real-world benchmark for contextualizing forthcoming PROTEUS results and informing risk-a...

Can Aydogdu, Benso John, Clara Seizer et al. · 0 citations
Open access Aug 2026

Radical Prostatectomy Without Prior Biopsy? Final Histopathology of Radical Prostatectomies in 103 Consecutive Biopsy-naïve Patients Who Underwent Radical Prostatectomy.

BACKGROUND AND OBJECTIVE Prostate biopsy for histological confirmation is the standard before radical prostatectomy (RP). However, some patients refuse biopsy despite highly suspicious imaging findings. This study aimed to evaluate final pathology, assess potential active surveillance (AS) eligibility, and exploratoril...

Marie Semmler, Julian Marcon, E. Berg et al. · 2 citations

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