Genetic predisposition to IL-1α autoantibodies is associated with reduced risk of rheumatoid arthritis and certain cancers, whereas genetic predisposition to IL-6 autoantibodies is associated with increased risk of diabetes, mirroring prior clinical observations.
J. V. von Stemann, Joseph Dowsett, R. Teglgaard et al.· Nature Communications· 0 citations
Polygenic risk scores stratifies lifetime adenoma and CRC risk and may inform risk-based screening initiation and intensity but adds limited predictive value when combined with FIT.
A. Nøhr, M. G. Overby, M. Nielsen et al.· British Journal of Cancer· 0 citations
BPD showed the strongest positive genetic correlations with GWAS of post-traumatic stress disorder, depression, attention deficit hyperactivity disorder, antisocial behavior, antisocial behavior, and measures of suicide and self-harm.
F. Streit, S. Awasthi, Alisha S. M. Hall et al.· Nature Genetics· 1 citation
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