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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

C. Carapito

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Open access Sep 2026

ER proteostasis failure in HYOU1 deficiency alters B cells, neutrophils, and interferon signalling

Multi-omics characterization of 2 patients with biallelic HYOU1 variants reveals that HYOU1 deficiency impairs the unfolded protein response, disrupts early B cell development, and alters neutrophil granulation as well as IFN signalling, further establishing ER proteostasis as a contributor to human immune homeostasis.

Aida Idani, S. Bibi-Triki, Tristan Stemmelen et al. · 0 citations
2027

Purification of C/D-Box snoRNP and Fibrillarin-Associated Factors from Arabidopsis thaliana Plants Using GFP-Tagged Proteins.

A protocol-detailed herein-combining the immunoprecipitation of a fibrillarin-Yellow Fluorescent Protein (FIB2-YFP) fusion protein in Arabidopsis thaliana with high-sensitivity liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis is developed.

J. Azevedo-Favory, S. A. Neumann, M. Rompais et al. · 0 citations
Open access Sep 2026

Pharmacological targeting of bunyavirus-induced synaptic impairment prevents neuronal hyperexcitability

Orthobunyaviruses are linked to a broad spectrum of neurological disorders. However, the molecular determinants governing bunyavirus neuropathogenesis remain poorly understood, precluding the identification of drugs able to alleviate virus-induced neuronal dysfunctions. Here, we show that the prevalent, yet neglected,...

Barbara Gorda, Jules Bouget, Vaishali Saini et al. · 0 citations
Open access Sep 2026

Sulfur source-driven global remodeling of gene expression in the fuel-biodesulfurizing Rhodococcus qingshengii IGTS8

The growth phase-dependent transcriptomic rearrangements under biodesulfurization conditions appear to prioritize cellular homeostasis and protection rather than proliferation, and the strongest transcriptomic response was evident during the late-log phase.

Ashraf M. El Nayal, V. Sangal, A. Alioua et al. · 0 citations
Open access Aug 2026

narrowPASEF: A Sample-Aware diaPASEF Method Optimization Strategy Improving Differential Proteomics Performance on Low-Abundance Proteins.

A sample-aware diaPASEF method optimization strategy for a timsTOF platform that demonstrates the most substantial impact on low-abundance proteins and provides an opportunity for a more precise and comprehensive analysis of the biological functions of biomarkers.

J. Rijal, Imane Charmarke Askar, Aurélie Hirschler et al. · 0 citations
#protein folding Open access Oct 2026

Polyploid Achromatium sp. expresses protein variants based on environmental cues

This work incubates freshly collected freshwater Achromatium under three temperature conditions and provides the first indication that Achromatium uses distinct protein variants under different environmental conditions, enabling it to swiftly respond to environmental changes through differential expression from its cac...

Sophie-Luise Heidig, Sunu Lama, J. Rijal et al. · 0 citations

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