PS1-1. Introducing Gene-Editing Semen for the Slick Mutation to Mitigate Fescue Toxicosis in Angus Cattle.
Tall fescue pastures support 40% of U.S. cow-calf herds, but fescue toxicosis causes heat stress and reduces animal performance and welfare. A mutation in the prolactin receptor (Slick mutation) gives cattle a sleek hair and reduces body temperature. This mutation does not occur naturally in Angus cattle, but can be...