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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Bu-Yong Ma

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#gene editing Oct 2026

Molecular dynamics simulation and QM/MM study of IscB-ωRNA complex.

The CRISPR-Cas9 system's gene-editing fidelity relies on the HNH nuclease domain's ability to hydrolyze DNA via metal-ion catalysis. While IscB-ωRNA variants offer advantages for viral delivery due to their small size, their editing efficiency is much lower than that of Cas9. The understanding of how HNH-domain dynamic...

Amina Abula, Gang-Gang Bai, Jing-Jing Li et al. · 0 citations
Open access Sep 2026

SynerHyper: Predicting Anticancer Drug Synergy for Lung Cancer Using Uni-Mol Enhanced Hypergraph Neural Networks and Multimodal Fusion

Lung cancer remains a leading cause of cancer-related mortality worldwide, and combination therapy is an important strategy for improving treatment efficacy and overcoming drug resistance. However, identifying synergistic drug combinations remains challenging because of the large combinatorial search space and the stro...

Chuan-Ce Sun, Ling-Hao Zhang, Xiao-Tang Huang et al. · 0 citations

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