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Author

Briar Bell

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Open access Jul 2026

Cryo-EM insights into isoform-specific properties of the IP3R2 channel

Cryo-EM structures of human IP3R2 are determined and mechanisms of IP3R2 activation and subtype-specific regulation are revealed, providing a framework for understanding isoform-dependent Ca2+ signaling.

M. R. Baker, Xiao-Xuan Lin, G. Fan et al. · 0 citations

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