Bret N. Smith

Lack of tau expression modifies epileptogenesis associated neuroplasticity in the ventral dentate gyrus in a mouse model of temporal lobe epilepsy

Investigation of how development of TLE modifies excitability and synaptic transmission in DGCs of the ventral dentate gyrus, distant from the kainate lesion, shows that development of TLE increases evoked action potential firing of ventral DGCs in mice that develop TLE, demonstrating an effect of TLE development on ex...