Constructing an Adenine Base Editor in Escherichia coli for Fine-Tuning the 1,4-Butanediamine Biosynthetic Pathway
The engineered strain achieved a marked increase in 1,4-butanediamine production, demonstrating that promoter editing via ABE can effectively regulate metabolic flux and enhance the production of the target product, as well as serving as a valuable reference for the biosynthesis of other high-value-added chemicals.
Yan-Ling Sun, Dicheva Ma, Ke Zhao et al.
· Microorganisms · 0 citations