Synergistic Variants in C-terminal Binding Protein 1 and Alkaline Phosphatase Lead to Mandibular Hypoplasia Through Impaired Wnt Signaling: An Oligogenic Model
A novel role for Ctbp1 is uncovered in craniofacial development and the complex genetic and molecular signaling in the pathogenesis of craniofacial malformations is highlighted.
P. Iyyanar, Beulah Solivio, K. Weaver et al.
· bioRxiv · 0 citations