Sep 2026
Pathological Th2 cell activation via STAT6 pathway for pulmonary fibrosis.
A CD28-JAK1/STAT6-Th2-monocyte-derived alveolar macrophage pathway is defined as a mechanistic driver of pulmonary fibrosis and nominate CD28 and STAT6 as actionable immunologic targets that could complement existing antifibrotic therapies.
Yudai Miyashita, T. Kaiho, Raul Piseaux Aillon et al.
· American Journal of Respirat... · 0 citations