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Author

B. Padmanabhan

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Sep 2026

Cannabinol β-O-Glucoside Inhibitors of the Keap1-Nrf2 Interaction: A Novel Therapeutic Strategy for Parkinson’s Disease

Computer analyses supported its Keap1-targeting activity, identifying CS-11 as a promising Parkinson’s disease therapeutic candidate and showing the strongest neuroprotective effect in a Parkinson’s disease model.

P. Deshmukh, Snehal U. Aouti, Ashok Sridhar et al. · 0 citations
Open access Sep 2026

Fragment-Based Discovery of BRD4-BD2 Selective Binders: Biophysical Validation and Structural Insights for Domain-Selective Inhibitor Design

BRD4, a member of the bromodomain and extra-terminal (BET) family of epigenetic readers, plays a central role in transcriptional regulation and is implicated in a wide spectrum of diseases. Although BRD4 inhibitors targeting both bromodomains have advanced into clinical studies, their development and therapeutic use...

Sriram Prakash Baskaran, Yashini Vidhya Subramani, S. Bairy et al. · 0 citations

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