Application of CRISPR–Cas9 technology in the treatment of chronic lymphocytic leukemia with mutant P53 gene
Aim This study proposes the implementation of clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein 9 (Cas9) technology for gene therapy targeting genetic mutations of P53 gene in human lymphocytes affected by chronic lymphocytic leukemia, (CLL), offering new opportunities for eff...