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Author

Aodong Qiu

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Aug 2026

A Time-Resolved Single-Cell Atlas Reveals Infection-Status, Age-, and Sex-Dependent Immune Responses Drive Viral Disease Severity

Time-resolved single-cell RNA sequencing across 16 conditions spanning age, sex, and four stages of influenza infection in mice generates a high-resolution atlas, revealing how infection status of the cell, age, and sex interact to drive persistent inflammation and impaired resolution.

Lu-Jia Chen, Aodong Qiu, Jooyoung Kim et al. · 0 citations
Open access Jul 2026

Knowledge-guided contextual gene set analysis with large language models

Abstract Motivation Gene set analysis (GSA) is a foundational approach for interpreting genomic data of diseases by linking genes to biological processes. However, conventional GSA methods overlook clinical context of the analyses, often generating long lists of enriched pathways with redundant, nonspecific, or irrelev...

Zhizheng Wang, Chi-Ping Day, Chih-Hsuan Wei et al. · 1 citation · ⚡1

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