Allelic replacement of the hexose transporter gene Lr67 by prime editing mimics natural durable resistance to leaf rust in hexaploid wheat
This study describes the development and application of a wheat-compatible prime-editing system to introduce the Lr67-associated TaSTP13(G144R) resistance allele into the A, B, and D TaSTP13 homoeologs of hexaploid wheat. Edited lines were generated and characterized for editing efficiency, followed by evaluation of le...