PS10-4. Effect of Mutating Porcine CYP17A1 for Altering Pregnenolone Metabolism to Control Boar Taint.
Cytochrome P450 17A1 (CYP17A1) interacts with cytochrome b5A (CYB5A) to regulate the metabolism of pregnenolone into 17α-hydroxypregnenolone (17OHP) and dehydroepiandrosterone (DHEA), androgens associated with superior growth performance in boars, or 5α-androst-16-ene-3-one (androstenone), a 16-androstene (16A) stero...