AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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ADAR-based RNA editing of specific sites in Variant 2’s mRNA leader is used, increasing translation of the gene and providing a novel avenue to rescue the loss-of-function phenotype in disease.
This study provides overall insight into the novel cleavage mechanism of the highly conserved family of YicC-like endoribonucleases, which can bind RNA hairpin structures and dimeric conformations with appropriate sequence and structural constraints.
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