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Alexis M. Gautreau

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#gene editing Aug 2026

Oncogenic PIK3CA enhances collective migration of mammary epithelial cells through ERK wave propagation.

Analysis of factors regulating collective cell migration of genome-edited MCF10A cell lines carrying hotspot PIK3CA mutations suggest that polarized actomyosin contractility and pulsatile ERK activation must be constrained in the territory of a phase diagram compatible with mechanotransduction of ERK waves across cell-...

A. Dayoub, A. Fokin, S. Leonov et al. · 1 citation

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