Author

Aleksandra Trifunovic

2 papers indexed here

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Open access Oct 2026

Gut Microbiota Fuel Aging Induced by Mitochondrial Dysfunction

It is found that microbiota promote host early-life fitness, at the cost of amplifying metabolic stress and inflammation later in life, and postulate that microbiota promote host early-life fitness, at the cost of amplifying metabolic stress and inflammation later in life.

Francesca Solagna, D. Martínez-Martínez, Norma Gabriela Zavala-Torres et al. · bioRxiv · 0 citations

Review Open access Sep 2026

Mitochondrial CLPP in Health and Disease: Mechanisms, Therapeutic Duality and Emerging Opportunities

This review discusses the physiological functions and substrate selectivity of CLPXP, the mechanistic basis and clinical development of CLPP inhibitors and activators, and the growing evidence that therapeutic responses depend strongly on tissue identity, metabolic state and the nature of the underlying mitochondrial d...

L. Isermann, Aleksandra Trifunovic · Journal of Inherited Metabol... · 0 citations