Aug 2026
A Time-Resolved Single-Cell Atlas Reveals Infection-Status, Age-, and Sex-Dependent Immune Responses Drive Viral Disease Severity
Time-resolved single-cell RNA sequencing across 16 conditions spanning age, sex, and four stages of influenza infection in mice generates a high-resolution atlas, revealing how infection status of the cell, age, and sex interact to drive persistent inflammation and impaired resolution.
Lu-Jia Chen, Aodong Qiu, Jooyoung Kim et al.
· bioRxiv · 0 citations