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Author

A. Yurttaş

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6 papers indexed here

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Open access Sep 2026

Midazolam Reduces Metabolic Viability and Induces Apoptosis in MIA PaCa-2 Pancreatic Cancer Cells with Selective Transcriptional Modulation of Wnt and Hedgehog Components: A Preliminary In Vitro Study

Background. Pancreatic ductal adenocarcinoma remains difficult to treat and has an exceptionally poor prognosis. While prior studies have noted antitumour properties for midazolam in pancreatic cancer, whether this response involves developmental signaling pathways is unclear. Here, we evaluated midazolam-treated MIA P...

Irmak Fatoş Korkmaz, T. Elgun, Ç. Aktaş et al. · 0 citations
Open access Sep 2026

Routine Vitamin and Iron Biomarkers Do Not Explain Variation in Anti-Müllerian Hormone: Implications for Ovarian Reserve Testing in Clinical Practice

Background: Anti-Müllerian hormone (AMH) is a key biomarker of ovarian reserve, reflecting the quantity of the remaining follicular pool. While chronological age is the primary determinant of AMH concentrations, emerging evidence suggests that vitamin D, vitamin B12, folate, and iron metabolism parameters may also infl...

Mete Hakan Karalök, Bağnu Dündar, Ayhan Parmaksız et al. · 0 citations
Open access Sep 2026

Method Comparison of Three Automated D-Dimer Assays

Background and Objective: D-dimer results differ across analytical platforms, which may affect their clinical interpretation. This study aimed to compare the analytical agreement and threshold-based classification of three routinely used D-dimer analyzers. Methods: Of 150 consecutive residual citrated plasma specimens,...

Bağnu Dündar, Betül Özbek Kurtul, B. Badilli et al. · 0 citations
Open access Sep 2026

Method Comparison of PT, INR, and aPTT Results Obtained Using Two Coagulation Analyzers in Routine Laboratory Practice

The two analyzer–reagent systems showed positive analytical associations, but the magnitude and dispersion of paired differences varied by assay, but the magnitude and dispersion of paired differences varied by assay.

Betül Özbek Kurtul, Bağnu Dündar, G. Gündoğan et al. · 0 citations
Open access Sep 2026

Melatonin Differentially Modulates Temozolomide Responses in Glioblastoma and Endothelial Cells: Associations with Global DNA Methylation and Cortistatin Levels

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and remains highly resistant to current therapeutic strategies. Temozolomide (TMZ) is a standard chemotherapeutic agent used in GBM treatment; however, intrinsic and acquired resistance limits its efficacy. This study investigated treatment-associa...

G. Gundogan, A. Yurttaş, Y. Oltulu et al. · 0 citations
Review Open access Aug 2026

Age and Follicle-Stimulating Hormone as Variables Independently Associated with Serum Anti-Müllerian Hormone in Women Attending a Tertiary Gynaecology Clinic: A Retrospective Cross-Sectional Study Using Censoring-Aware Modelling

Objective: Anti-Müllerian hormone (AMH) is the most widely used biochemical marker of ovarian reserve, but its associations with other reproductive hormones are usually examined one hormone at a time and without accounting for values reported at the assay floor. This study examined the associations between serum AMH an...

Mete Hakan Karalök, Bağnu Dündar, Ayhan Parmaksız et al. · 0 citations

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