Author

A. Vilella

2 papers indexed here

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Open access Oct 2026

Chronic Inhalation of Sulphureous Water Mitigates Early Amyloid Pathology and Associated Microglial Changes in 5XFAD Mice

Background: Alzheimer’s disease (AD) is a chronic neurodegenerative disorder characterized by progressive cognitive decline and behavioral impairments. Hydrogen sulfide (H2S) is an endogenous gasotransmitter that exerts pleiotropic neuromodulatory, anti-inflammatory, cytoprotective, and trophic effects within the centr...

Martina Bodria, Eleonora Daini, Stefano Pioli et al. · Brain Science · 0 citations

Open access Sep 2026

CX3CL1-CX3CR1 signaling shapes the sex- and region-dependent neuroimmune response to LPS: Impact on plasticity and kynurenine pathway metabolism in the hippocampus.

BACKGROUND Fractalkine signaling is a central mediator of neuron-microglia communication. We previously demonstrated that, under physiological conditions, the fractalkine receptor (CX3CR1) differentially modulates synaptic plasticity along the dorsoventral axis of the hippocampus in male but not in female mice. During...

Eleonora De Felice, Giovanni Signorini, Laura Bertarini et al. · Brain, behavior, and immunit... · 0 citations