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Hyperlipidaemia is a major modifiable risk factor for cardiovascular disease and remains a global health concern. Although conventional lipid-lowering drugs are effective, their long-term use is often associated with adverse effects, prompting interest in safer dietary alternatives. Flavonoids, such as quercetin, narin...
INTRODUCTION Chronic liver injury results from persistent hepatic injuries such as metabolic disorders, alcohol consumption, viral infections, drug toxicity, autoimmune conditions, and genetic factors. It is a major global health concern due to its progression to fibrosis, cirrhosis, and hepatocellular carcinoma. This...
INTRODUCTION Inflammatory and immune-mediated kidney disorders (IMKD) comprise a diverse group of renal diseases and are a leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide. Despite advancements in supportive care, longterm renal outcomes remain suboptimal due to disease heterog...
INTRODUCTION The tropical plant Carica papaya L., which is a member of the Caricaceae family, is well known for its medicinal and nutritional qualities. The plant's leaves, fruits, seeds, and latex have all historically been used to treat inflammatory diseases, cancer, metabolic abnormalities, and infections. The objec...
Overall, biologic therapies have transformed the management of severe asthma by enabling more individualized treatment strategies, improving disease control, reducing exacerbation risk, and enhancing long-term clinical outcomes.
Current evidence indicates that effective LSDV control requires integration of molecular diagnostics, vector management, vaccination, and host immunogenetics, and BoLAguided immunoinformatics provides promising opportunities for developing multi-epitope vaccines, although experimental validation remains essential.
Although C. citrinus has remarkable therapeutic promise, the paucity of clinical studies and pharmacokinetic data, and the lack of standardization hinder its clinical translation, and there is a need for clinical trials to prove its potential therapeutic benefits.
The integration of QSRR, ML, and DoE offers a viable foundation for developing RP-HPLC methods for antiviral drug analysis that are predictive, effective, and environmentally friendly.
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