Mutation-induced phenotypic plasticity drives formation of a pro-metastatic tumour-intrinsic niche
It is argued that formation of a tumour-intrinsic niche is a prerequisite for BRAF-mutant CRC seeding to distant organs and that interference with niche formation may help avoid metastatic relapse.
J. Bugter, L. El Bouazzaoui, E. Küçükköse et al.
· bioRxiv · 2 citations