Intrinsically disordered regions in eukaryotic mRNA decay pathways.

RNA‐Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities

A network‐based framework for exploiting RBPs as therapeutic vulnerabilities and for advancing next‐generation precision oncology is provided, integrating mechanistic principles with translational evidence.

Beyond the structure-function paradigm: A comprehensive review of intrinsically disordered proteins

A cross-kingdom synthesis of disorder-based chromatin regulation is developed, demonstrating that bacterial nucleoid-associated proteins, plant transcription factors, and mammalian chromatin regulators share a conserved charge-regulatory logic, mediated by PTM-dependent mechanisms that dynamically couple environmental...

Bacterial small regulatory RNAs.

The regulatory functions of bacterial sRNAs are summarized, the molecular mechanisms that govern their expression and regulatory consequences are described, and the many exciting open questions surrounding sRNA-mediated gene regulation in bacteria are discussed.

Experimental and Computational Approaches to Identify RNA–Protein Interactions

Comparisons of experimental techniques and computational prediction tools for RBP identification aim to facilitate more accurate mapping of RNA–protein interactomes, thereby advancing understanding of RBP functions and supporting the development of novel therapeutic interventions targeting RNA–protein complexes.

Annual Review of Cell and Developmental Biology mRNA-Scaffolded Cytoplasmic Compartments

Bioinformatic pipeline to identify candidate mRNA transcripts targeted by the putative Regulated Ire1-Dependent Decay pathway of Dictyostelium discoideum .

A bioinformatic pipeline is developed that identified 21 mRNA transcripts of D. discoideum that contain a consensus Ire1 cut site found within a secondary mRNA hairpin loop structure and have the potential to be cut by IreA.