TL;DR
Common rules governing host–virus interactions across life are outlined, outlining universal principles of pathogen sensing, signalling and effector function that reveal common rules governing host–virus interactions across life.
Arboviruses encompass a diverse spectrum of arthropod-transmitted RNA viruses that pose an extensive threat to human health and the economy. These obligate intracellular pathogens induce severe pathologies by strategically subverting the host's innate immune responses, often leading to a plethora of clinical manifestat...
This review examines the diverse yet convergent immune evasion strategies employed by major neurotropic RNA and DNA viruses, including herpes simplex virus, varicella-zoster virus, cytomegalovirus, rabies virus, rabies virus, flaviviruses, alphaviruses, enteroviruses, and JC virus.
This Review summarizes current knowledge of how the innate immune system recognizes ZIKV and how the virus counteracts these responses, while highlighting unresolved questions and potential therapeutic targets.
This review synthesizes current evidence to show that phylogenetically diverse ESKAPE pathogens have convergently evolved conserved strategies to evade host immunity under comparable selective pressures, and identifies conserved host-directed therapeutic targets that may complement conventional antimicrobial therapy ac...
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