Development of Pyrazole and Acyl Hydrazone Derivatives as Potential Anticancer Agents: A Combined DFT and Molecular Docking Approach

Mohammed Al-Ghorbani Osama Alharbi W. Alsaedi Abdel-Basit M. Al-Odayni A. Alrahlah Ajay Thakur Saif H. Althagafi M. Ibrahim R. Ramu

Aug 2026 · Russian journal of bioorganic chemistry · Vol 52 · 0 citations · 48 references

TL;DR

The demonstrated cytotoxicity and molecular interaction profiles offer a valuable structural and electronic rationale for the design of next-generation anticancer therapeutics and underscore the potential of these dual scaffolds as targeted kinase inhibitors.

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