Study of Genetic Resistance to Scrapie in Sheep of the Gene Pool Herd of the Southern Meat Breed and in Their First Generation (F1) Crossbreeds with Katumskaya Breed by the Prion Protein Gene (PRNP)

Polymorphism of Prion Protein Gene and Evaluation on Genetic Risk for Scrapie in Three Native and One Introduced Breed in the Republic of North Macedonia

Abstract Transmissible spongiform encephalopathy in sheep is known as scrapie. Polymorphisms at codons 136, 154, and 171 of the prion protein (PRNP) gene are associated with resistance or susceptibility to the disease. Based on allele combinations, sheep are classified into five genetic risk groups. The aim of this stu...

DNA MARKERS FOR EVALUATING THE ADAPTATION POTENTIAL OF RABBITS AND FUR-BEARING ANIMALS

Modern breeding of agricultural animals has transitioned from phenotype-based selection to high-precision genomic prediction based on hundreds of thousands of DNA markers. This has not only accelerated the development of breeds with target traits but also enhanced their adaptability and stress resistance through the de...

Characteristics of genetic resistance to Maedi-Visna in sheep breeds raised in Russia

Relevance. Small Ruminant Lentiviruses (SRLVs), including the Visna-Maedi Virus (VMV) in sheep, induce chronic progressive inflammation primarily targeting the nervous system, lungs, mammary glands, and joints. These viruses exhibit significant genetic variability, leading to a lack of effective therapies or vaccine...

Analysis of Inbreeding, Population Structure, and Genetic Diversity in the Kumamoto Sub-Breed of Japanese Brown Cattle

Simple Summary The Kumamoto sub-breed of Japanese Brown cattle is a local beef cattle population in Japan. It is facing increasing inbreeding and a declining effective population size because of the intensive use of a limited number of elite sires. This study used genetic marker information from 811 cows to evaluate in...

Genotyping the self-incompatibility locus of wild and cultivated Brassica using NGS technologies: application to the evaluation of mate limitation in the endangered species Brassica insularis

Optimization of SCoT and iPBS-Retrotransposon Marker Systems for PCR-Based Genetic Analysis in Alfalfa (Medicago sativa L.)

The correct selection and appropriate optimization of molecular markers and primers used in genetic diversity studies are crucial for the unveiling of true polymorphism among genotypes and to make sure that the data obtained can be used effectively in breeding programs. Two important molecular marker systems that are w...