Sep 2026· International Research Journal on Advanced Engineering Hub (IRJAEH)· 1 citation
Artificial Intelligence in Healthcare
TL;DR
An ensemble learning-based framework for improved heart disease prediction using multiple datasets and Explainable Artificial Intelligence (XAI) to evaluate model performance in terms of the clinical features that are most relevant in predicting heart disease.
Abstract
Heart disease is a serious threat to human health; it is one of the leading causes of death. Being able to predict it in advance can help doctors separate patients into different categories based on risk levels and provide the most needed care to those who require it most. One of the ways to predict it is using the machine learning method. However, it should be noted that there are some issues with such models, such as overfitting, noise sensitivity, and sometimes a relatively low predictive performance. To address these limitations, this proposed study aims to develop an ensemble learning-based framework for improved heart disease prediction using multiple datasets. In this study, different machine learning classification algorithms will be implemented and evaluated. Ensemble techniques, particularly voting and stacking, will be investigated by combining the predictions of multiple diverse base classifiers The proposed study will adopt the following procedure: data pre-processing, selection of predictive features, data normalization, model training, hyperparameter optimization, and performance evaluation. The following performance metrics will be used to assess the models’ performance: accuracy, precision, recall, F1-score, specificity, and ROC-AUC. The methods mentioned above will be used to test, analyze, and confirm the reliability of results. Moreover, we will apply Explainable Artificial Intelligence (XAI) to evaluate model performance in terms of the clinical features that are most relevant in predicting heart disease. We will use SHAP (SHapley Additive exPlanations) as XAI for interpreting the results. The proposed framework is expected to improve prediction accuracy and robustness compared the proposed study examines the effectiveness of ensemble learning and explainable artificial intelligence algorithms to predict heart disease risks and provide decision-making support to healthcare practitioners.
The proposed hybrid and explainable machine learning architecture demonstrates substantial predictive accuracy, robustness, and interpretability for the early detection of heart disease.
Sudipta Bhattacharya, Bingshati Mondal, Nabanita Das et al.· Recent Advances in Computer...· 0 citations
Though technology is extensively applied to medical field, it remains one of the most urgent problems of healthcare sphere as heart diseases are complicated by the interplay of clinical, behavioral, and physiological causes. This research is aimed at suggesting a machine learning framework that can provide accuracy, tr...
Vishal Bharadwaj Meruga, Venkata Reddy Medikonda, Rama Krishna Eluri et al.· International Conference on...· 0 citations
A robust Ensemble Learning (EL) framework for the prediction and classification of CVD by integrating multiple ML algorithms with a DL component using an Artificial Neural Network employed as a feature extraction layer prior to ensemble aggregation is presented.
El Haddad Khadija, A. Bekkari, W. Bouarifi et al.· Engineering, Technology &...· 0 citations
A robust and explainable machine learning framework based on a stacked ensemble model that uses Random Forest, Support Vector Machine, and Gradient Boosting as base learners and Catboost as the meta-learner to support more informed and trustworthy decision-making in healthcare applications is presented.
The research work concludes that ML models, when properly tuned and validated, can significantly assist in the early diagnosis of heart disease, offering critical support for clinical decision-making.
The high performance highlights the effectiveness of advanced ensemble learning in achieving reliable heart disease predictions, emphasizing the potential of integrating robust feature selection with sophisticated classification models for precise medical data analysis.
Manoj Kumar Konudula, S. K, R. M· Advanced International Journ...· 0 citations
Related blog posts
MIT News · Artificial Intelligence· news.mit.eduNov 2, 2026
The MIT professors collaborated to identify the first AI-discovered antibiotic, a scientific breakthrough that is widely recognized as a milestone in AI-driven drug discovery.
MIT News · Artificial Intelligence· news.mit.eduOct 30, 2026
MIT professors Adam Berinsky and Chara Podimata discuss a new project to track how AI chatbots are responding to questions about the 2026 U.S. midterm elections.