Genome mining reveals an architecturally expanded pyoluteorin-associated biosynthetic gene cluster and a divergent flavin-dependent halogenase-like sequence in deep-sea Pseudomonas Aeruginosa from the Gulf of Guinea
This study provides the first comprehensive genomic characterisation of a pyoluteorin-BGC-harbouring marine P. aeruginosa strain, demonstrating conservation of the core biosynthetic machinery alongside an expanded transport architecture and a divergent FDH-like sequence that may represent a candidate for future biochemical investigation.
Siderochelin A, a monomeric compound isolated from a fermentation product, demonstrated antibacterial efficacy against various pathogenic bacteria, providing a theoretical basis for discovering novel species, exploring secondary metabolites, and developing innovative antibiotics.
Yi-Huang Chen, Lu-Yao Wang, Tao Luo et al.· Microorganisms· 0 citations
The isolation of a novel Jiangella strain reported from a marine, animal-associated plastisphere is described and its biosynthetic repertoire is placed in the context of the whole genus, providing a genome-based prioritization of candidate biosynthetic targets.
Ruggero Baviera, F. Capri, Paola Galluzzo et al.· Marine Drugs· 0 citations
The putative biosynthetic pathway of the paenialvins is described and structural variations are explained, bringing useful data on Paenibacillus secondary metabolism for future antibiotic development.
Drago Haas, Fatoumata Tambadou, T. Caradec et al.· Probiotics and Antimicrobial...· 0 citations
B. sanguinis AZMABM HM27 represents a marine symbiotic strain associated with R. magnifica and a promising source of bioactive compounds with antioxidant, anti-inflammatory, antidiabetic, and antiproliferative potential.
B. Manguntungi, Feraliana Feraliana, Azzahra Khasna Ramaniya et al.· Molecular Biology Reports· 0 citations