Clinical characteristics and predictors of severe pertussis in hospitalized children after the COVID-19 period in Türkiye: a multicenter study

Sevliya Ocal Demir Pınar Canizci Erdemli Esra Çakmak Taşkın Ayşe Tekin Yılmaz Semra Bayturan Şen Deniz Ergün Hincal Ozbakir Berna Çetin Kahraman Canan Özlü Berker Okay H. Hatipoğlu Suleyman Bayraktar H. K. Konca Seval Özen Pınar Bayraktar Hatice Karaoğlu Asrak Duygu Tunçel Faysal Göçeri Demet Tosun M. Menentoğlu N. Hatipoğlu M. Sütçü Bilge Aldemir Kocabaş Muhammet Köşker Gülperi Timurtaş Dayar Seyhan Yılmaz Burcu Parlak C. Çetin A. Karaaslan Lutfiye Sahin Keskin N. Dalgıç Burcu Bursal Nihal Akçay Yağmur Ilgar Mustafa Gençeli Özge Metin Akçan Sevgi Pekcan Belkıs Hatice Inceli H. Özdemir E. Çiftçi Merve İşeri Nepesov Erdal Sarı Sevgi Yaşar Durmuş Binnaz Çelik Ayper Somer A. Büyükçam Mavera Uşaklıoğlu Erol Â. Karbuz Çiğdem Kırmacı Vildan Şahin Şefika Elmas Bozdemir Ö. F. Kızılsoy Murat Tutanç Sevgi Aslan Tuncay Aylin Dizi Işık M. Emiroğlu Meltem Kiymaz Z. G. Gayretli Aydın Gülben Özgül Postuk Önder Kılıçaslan A. Şahin Güldane Dikme Edanur Yeşil Merve Kılıç Çil Dicle Şener Okur E. Salı D. Çakır Elif Gudeloglu Selcuk Sinanoglu Emine Hafize Erdeniz Canberk Çınar Hatice Sınav Ütkü Selim Öncel Yıldız Ekemen Keleş D. Geçkalan Nesli Ağralı Eröz Ahu Kara Aksay Dilek Yılmaz Didem Büyüktaş Aytaç Meryem Çağla Abacı Çapar Mehlika Efendi Kocagöz O. Turel A. Güney Gülhadiye Avcu D. Terek Cihangul Bayhan I. Ecevit M. Kara Hülya Ercan Saricoban Ece Orbay Deniz Aygun Eda Karadag-Oncel Şilem Özdem Alataş Tuğba Kandemir Gülmez Gizem Mardinoğlu Ömer Kılıç Taylan Çelik Tolga Kasap Eda Somuncu S. Kara G. Arga Eda Kepenekli̇ G. Akkoç

Jul 2026 · European Journal of Pediatrics · Vol 185 · 0 citations · 64 references

Medicine

TL;DR

Severe pertussis predominantly affects young infants, and apnea, respiratory distress, and leukocytosis were identified as major predictors of severe disease and incomplete vaccination is associated with increased disease severity.

DOI PubMed Semantic Scholar

View source

Similar papers

Clinical and Laboratory Predictors of Disease Severity in Hospitalized Children with COVID-19: A Study from the Early Pandemic Period

The aim of this manuscript is to evaluate the clinical, laboratory, and radiological characteristics of hospitalized children with COVID-19 and to compare findings according to disease severity, to understand risk factors associated with severe disease, particularly in upper-middle-income healthcare settings.

A. Boğa, Elif Betül, Keskin Çetinkaya et al. · 0 citations

Open access Sep 2026

Clinical Outcomes in Pediatric COVID‐19 Across Two Time Periods: The Role of Coinfection, Age, and Inflammatory Markers

Pediatric COVID‐19 outcomes appear to be mostly influenced by coinfections, lower respiratory tract involvement, and younger age, with newborns being the most vulnerable group.

E. Turanlı, Sema Yıldırım Arslan, Fatih Dinc · Journal of Medical Virology · 0 citations

Open access Sep 2026

Analysis of Clinical Characteristics of Pertussis in Children Aged 0–6 Years in Tertiary and Pediatric Hospitals of Jiangsu Province from January to May 2024

Objective: To analyze the clinical manifestations and hospitalization-related factors among children with pertussis, and to provide scientific support for pertussis prevention, control, clinical diagnosis, and treatment. Methods: From January through May 2024, children aged 0–6 years with a confirmed diagnosis of pertu...

Yan Xu, Mei Li, Qiang Chen et al. · Vaccines · 0 citations

Sep 2026

Pediatric invasive meningococcal disease in Türkiye during the post-pandemic period: increased reported cases and predominance of serogroup B and severity determined by a clinical form in a multicenter hospital-based cohort

Esra Çakmak Taşkın, G. Arga, B. Arslan et al. · European Journal of Pediatri... · 0 citations

Open access Sep 2026

Clinical Course and Outcomes of Complicated Community-Acquired Pneumonia in Children During a 5-Year Period Including the COVID-19 Pandemic

The findings are consistent with the fact that vaccine breakthrough infections, including those caused by pneumococcal serotypes 3 and 14, may still contribute to severe cCAP, whereas group A Streptococcus was identified in a minority of culture-positive cases.

Irem Ceren Erbaş, Silem Ozdem Alatas, Ayse Cakil Guzin et al. · Turkish archives of pediatri... · 0 citations

Open access Oct 2026

Remdesivir use in hospitalized children with COVID-19: hepatic and systemic safety

Safety data regarding remdesivir in pediatric populations remain limited, particularly for those with complex comorbidities. This study evaluated the hepatic and systemic safety of remdesivir in hospitalized children with COVID-19 by comparing treated patients to a control group receiving no antiviral therapy....

Patrycja Puciato, K. Sequeira, В. В. Вартанян et al. · Pediatria Polska · 0 citations