Bavachinin exhibited anti-inflammatory and pro-apoptotic activities against HeLa cells, likely through oxidative stress-associated apoptosis and modulation of NF-κB-associated inflammatory gene expression.
NaHS exerts potent antiproliferative effects in colorectal cancer cells by inducing oxidative stress–mediated apoptosis and inhibiting key survival and inflammatory signaling pathways.
A. Öztürk, Şeyma Taştemur, Ahmet Ozan Kaleci et al.· Molecular Biology Reports· 0 citations
Enoxaparin exhibits multifaceted anticancer effects by promoting apoptosis and autophagy, selectively modulating inflammatory pathways, and reducing oxidative DNA damage in breast and liver cancer cells.
Sedat Çarkıt, M. Baran, N. Bitgen et al.· Scientific Reports· 0 citations
It is demonstrated that carvacrol effectively inhibits CRC growth while exerting limited effects on normal colon fibroblasts, which support the further investigation of carvacrol as a potential complementary therapeutic agent for CRC.
A. Abuaisha, H. Arslan, Emir Nekay et al.· Molecular and Cellular Bioch...· 0 citations
It is demonstrated that 8-gingerol induces coordinated apoptotic and ferroptotic cell death through a Ca2+-dependent ER stress mechanism, highlighting its potential as a novel therapeutic strategy for the treatment of ovarian cancer.
Tae Woo Kim· Cell communication and signa...· 0 citations
Acrylamide (Acr) is a widely encountered environmental and dietary toxicant known to induce oxidative stress and disrupt male reproductive function. Leydig cells, due to their high metabolic activity and mitochondrial dependence, are particularly vulnerable to redox imbalance. N-acetylcysteine (Nac), a thiol-containing...
Banu Orta Yilmaz, Iremnur Sarialioglu, Gokce Elmaci et al.· Drug and chemical toxicology...· 0 citations
It is demonstrated that API induces intrinsic mitochondrial apoptosis through oxidative stress-mediated mechanisms, providing mechanistic evidence for its cytotoxic effects and supporting its potential as a phytochemical candidate for uterine leiomyoma treatment.
Samak Sutjarit, C. Setthawongsin, C. Sakulthaew et al.· Toxicology Reports· 0 citations
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