Exploring the causal relationship and pathogenesis of intracranial aneurysms with osteoporosis based on Mendelian randomization and bioinformatics study.
This study identifies three genetic pathways linking biological aging to vascular disease, offering new molecular targets for its prevention and treatment.
Hao Yan, Shan Wei, Hui Hui et al.· Clinical and applied thrombo...· 0 citations
This MR study ruled out the causal relationship between OCC and lymphoma and identified a statistically significant inverse correlation between mature T/NK-cell lymphoma and OCC.
Yayan Deng, Min Kang· Oral Health & Preventive Den...· 0 citations
Observational research has found a relationship between gastroesophageal reflux disease (GERD) and hyperlipidemia (HLP). This study explored the relationship between GERD and HLP using bioinformatics and Mendelian randomization (MR) methods. We first conducted bioinformatics analyses to identify differentially expresse...
Observational studies have suggested a potential association between hypertension and frozen shoulder. This study aims to elucidate the causal dynamics of this relationship using a bidirectional 2-sample Mendelian randomization approach. We analyzed data on hypertension (N = 484,598) and frozen shoulder (N = 627,998) f...
Dan-Yun Hua, Ying-Ying Chen, Lu Wang et al.· Medicine· 0 citations
A significant causal relationship between alcohol-induced CP and elevated risks of myocardial infarction and large artery atherosclerosis stroke, and a causal link between CP and stroke as well as ischemic stroke are indicated.
Shi-En Shen, Yue-Nan Zhu, Jie-Qiong Lin et al.· Medicine· 0 citations
This study suggests that IL‐12p40 is probably one of the factors correlated with HT etiology, contributing to a better understanding of the pathogenesis of HT and underscoring the potential for therapeutic interventions targeting inflammatory proteins.
Shu-Ting Ding, Wei-Qiang Su, Ming-Hao Wu et al.· Mediators of Inflammation· 0 citations
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