Skip to content
Preprint

MSM-Mem: A Universal Medical Structured Multimodal Memory Framework for Medical AI Agents

Aug 2026 · 0 citations · 37 references
Computer Science

TL;DR

Medical Structured Multimodal Memory (MSM-Mem), an agentic memory framework that enables medical AI agents to evolve through accumulated clinical experiences, is proposed, offering a viable pathway toward medical AI agents capable of evolving their reasoning competence in a manner analogous to the way clinicians learn from practice over time.

Abstract

Clinical decision-making is inherently experience-driven: physicians progressively refine their reasoning by synthesizing patient history, multimodal observations, and prior diagnostic experiences across interactions. In contrast, current multimodal large language model (MLLM)-based medical AI agents largely operate as stateless inference systems, generating decisions independently for each interaction without retaining or internalizing experiential knowledge. This discrepancy limits their ability to progressively improve reasoning reliability through usage and adapt to longitudinal patient contexts in real-world clinical workflows. In this study, we propose Medical Structured Multimodal Memory (MSM-Mem), an agentic memory framework that enables medical AI agents to evolve through accumulated clinical experiences. MSM-Mem organizes heterogeneous clinical experiences into semantic, episodic, and visual memory and incrementally updates them during inference, allowing the agent to retrieve prior experiences to inform current reasoning and progressively refine decision-making over time. Evaluations on MoE-LLaVA backbones demonstrate consistent performance improve- ments with further gains observed through continued usage. In general, MSM-Mem offers a viable pathway toward medical AI agents capable of evolving their reasoning competence in a manner analogous to the way clinicians learn from practice over time.

View source

Similar papers

Preprint Sep 2026

From Given to Gathered Evidence: Agentic Learning for Longitudinal Medical Reasoning

Foundation models can serve as clinical agents through tool-use harnesses. However, conventional medical benchmarks assess reasoning over preselected evidence rather than the ability to seek it across clinical records and longitudinal imaging. We propose CASE: a series of role-specific Clinical Agents for Seeking Evide...

Min-Ye Shao, Chao-Hui Yu, Yi-Xuan Wu et al. · 0 citations
#artificial intelligence Preprint Sep 2026

EMR: Self-Evolving Medical Multi-Agent System via Experience Mining and Reuse

EMR introduces a hierarchical clinical experience library that organizes accumulated knowledge into three levels: clinical principles, diagnostic patterns, and representative cases, and reveals that the hierarchical experience enables cross-specialty generalization and transfer across diverse LLM backbones, offering a...

Dong-Sheng Shi, Yue Li, Xin Yi et al. · 1 citation
Aug 2026

Agentic Foundation Models for Explainable Multimodal Clinical Intelligence: A Human-Centered Framework for Early Disease Diagnosis and Personalized Treatment Planning

A framework that treats diagnosis as a coordination problem rather than a modeling one is described and improved on both across accuracy, F1-score, explanation faithfulness and clinician-rated trust, at an added latency of roughly five seconds per case.

Ganesh Dagadu Puri · 0 citations
Preprint Sep 2026

From Image Interpretation to Clinical Reasoning: Upstream Physician-Context-Aware Multimodal Learning with Causal Reinforcement Learning

Major adverse cardiovascular events (MACE) remain the leading cause of mortality worldwide. Opportunistic screening using routinely acquired clinical data offers a scalable approach for identifying high-risk individuals before acute events occur. Although chest X-rays (CXRs) capture latent cardiovascular biomarkers and...

Jia-Lu Pi, Ya-Nan Ma, Wei-Jie Chen et al. · 0 citations
Open access Sep 2026

Retrieval-augmented multi-agent framework for evidence-centric medical reasoning

This work proposes MRER (multi-agent reasoning with evidence retrieval), a multi-agent retrieval and reasoning framework inspired by evidence-based medicine that achieves an average accuracy and improves the logical coherence and trustworthiness of the generated reasoning.

Zi-Ming Gao, Wei Lu, Wan-Ting Zhu et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.