Skip to content
Log in
Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI
Open access

Associations Between Neuromuscular Fatigue, Anxiety, and Peripheral Biomarkers of Neuronal Injury, Inflammation, and Mitochondrial Dysfunction in Treatment‐Naïve Relapsing‐Remitting Multiple Sclerosis

Amanda V. Steckert Keli Dias Feltrin Luiz Fernando Silva Rodrigues F. M. Liz Maria Milena Figueiredo Muller Daniel Paulo Bortoluzzi Andréia Biolchi Mayer L. Ceretta Tatiana Barichello Felipe Dal-Pizzol D. Dominguini
Aug 2026 · Brain and Behavior · Vol 16 · 0 citations · 90 references
Medicine

Abstract

To investigate whether neuromuscular fatigue and anxiety are associated with a peripheral biological signature involving inflammation, oxidative stress, mitochondrial homeostasis, neurotrophic support, and neuronal/glial injury markers in treatment‐naïve patients with relapsing‐remitting multiple sclerosis (RRMS).

DOI PubMed Semantic Scholar
Read PDF

Similar papers

Review Open access Sep 2026

Inflammatory Correlates and Prospective Associations of Cancer‐Related Fatigue: A Systematic Review and Meta‐Analysis

Cancer‐related fatigue (CRF) is a prevalent and disabling symptom across the cancer continuum and is increasingly conceptualized as a biobehavioral symptom with inflammatory underpinnings. However, evidence linking specific circulating inflammatory biomarkers to CRF remains fragmented and inconsistent.

Li-Na Wu, Xing-Yu Xiong, Zhao-Hui Zhang et al. · 1 citation
Review Open access Aug 2026

Therapeutic Potential of Oxiracetam in Neurocognitive Disorders: A Narrative Review

This review aims to evaluate the mechanistic basis, clinical efficacy, and safety profile of oxiracetam as a potential therapeutic agent for cognitive dysfunction across a range of neurological disorders.

Hafsa Ali, Syeda Maliha, Sundas Ishtiaq et al. · 0 citations
Open access Sep 2026

Serum VIP and IL‐1β Levels Are Associated With Anxiety and Depression in Patients With Parkinson's Disease: A Cross‐Sectional Study

This study evaluated whether circulating concentrations of vasoactive intestinal peptide, interleukin‐1β (IL‐1β), and tumor necrosis factor‐alpha (TNF‐α) differed according to the presence of anxiety and depressive symptoms among individuals with PD.

Liang-Yu Li, Xiao-Yang Jia, Ying-Chang Shi et al. · 0 citations
Review 2026

Mechanism and Research Progress of Anti-Inflammatory Dietary Intervention in Tic Disorders and Their Comorbidities

: Tic disorder represents a prevalent neurodevelopmental disorder, yet conventional pharmacotherapy frequently causes notable adverse effects. Anti ‑ inflammatory diets show therapeutic promise for neuropsychiatric conditions through modulating gut microbiota and relieving neuro inflammation and oxidative stress. This...

Miao-Miao Gao, Qian Niu, Rui Jing · 0 citations
Open access Sep 2026

Protein Biomarkers in Risk and Prognosis of Amyotrophic Lateral Sclerosis

Plasma and cerebrospinal fluid (CSF) protein biomarkers in amyotrophic lateral sclerosis (ALS) may provide insight into disease mechanisms and yield clinically useful biomarkers.

Lu Pan, C. Hou, Christina Seitz et al. · 0 citations
Open access Sep 2026

Immune dysregulation in depression and psychosis: summary of current evidence and future perspectives.

Despite compelling epidemiological, genetic and cellular evidence linking immune dysregulation to depression and schizophrenia (and other psychotic disorders), causality remains contested and no immune biomarker has yet demonstrated robust clinical utility. Emerging methodological approaches - from target trial emulati...

T. Formánek, M. Lynall, E. Osimo · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.